A new study reveals that due to mutations in the OAS1 gene, a portion of the population is less susceptible to infection with the coronavirus or is completely protected from disease.
A group of scientists at the MRC University Virus Research Center in Glasgow (UK) discovered that the secret of this process lies in the process of hydrolysis, the process in which a hydrophobic molecule is added to a protein.
Such a modification allows the AOS1 gene to “search” for the invading virus and “sound the alarm”, according to The study published in the journal Science.
In addition, scientists have found that patients with a “bad” form of OAS1 You have serious COVID-19 Often times and they have a 1.6 times higher chance of dying than people with the previous gene.
Researchers claim that horseshoe bats were around 55 million years ago. Possible source of SARS-CoV-2, this protective gene was lost, so the virus did not have to adapt to avoid this defense.
However, researchers believe that New mutations of SARS-CoV-2 You can learn how to avoid protecting this gene. Their study showed that the coronavirus that caused the SARS outbreak from 2002 to 2004 learned to evade the previous OAS1.
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